For journal club, we'll be reviewing results from the "The Ischemic Optic Neuropathy Decompression Trial Research Group" as well as 5, 10 and 15 year data from the Optic Neuritis Treatment Trial
Optic nerve decompression surgery for nonarteritic anterior ischemic optic neuropathy (NAION) is not effective and may be harmful. The Ischemic Optic Neuropathy Decompression Trial Research Group. JAMA. 1995 Feb 22;273(8):625-32. PubMed PMID: 7844872.
The 5-year risk of MS after optic neuritis: experience of the optic neuritis treatment trial. 1997. Neurology. 2001 Dec;57(12 Suppl 5):S36-45. PubMed PMID: 11902594 Beck RW, Trobe JD, Moke PS, Gal RL, Xing D, Bhatti MT, Brodsky MC, Buckley EG, Chrousos GA, Corbett J, Eggenberger E, Goodwin JA, Katz B, Kaufman DI, Keltner JL, Kupersmith MJ, Miller NR, Nazarian S, Orengo-Nania S, Savino PJ, Shults WT, Smith CH, Wall M; Optic Neuritis Study Group. High- and low-risk profiles for the development of multiple sclerosis within 10 years after optic neuritis: experience of the optic neuritis treatment trial. Arch Ophthalmol. 2003 Jul;121(7):944-9. PubMed PMID: 12860795. Optic Neuritis Study Group. Multiple sclerosis risk after optic neuritis: final optic neuritis treatment trial follow-up. Arch Neurol. 2008 Jun;65(6):727-32. PubMed PMID: 18541792; PubMed Central PMCID: PMC2440583.