Ocular Bacterial Anti-Infectives
Anti-infectives are a vital part of the treatment of ocular bacterial infections that include endophthalmitis, keratitis, conjunctivitis, and

blepharitis. Ocular therapy differs from systemic therapy with the direct use of topical application to the ocular surface, subconjunctival injection, or the direct injection of anti-infectives into the intracameral chambers. Anti-infective susceptibility is interpreted using the systemic standards assuming that the anti-infective concentrations are greater in the ocular tissue than the blood serum. Using these concepts, this course will review the respective mechanisms of activity for different classes of anti-infectives for the treatment of Gram-positive and Gram-negative infections, and discuss the aspects for the development of new anti-infectives.
Regis P. Kowalski, MS, [M]ASCP

Please read the entire Pseudomonas keratitis paper.

For the disease papers (blepharitis, endophthalmitis, etc): Please read the introduction and tables for each paper.  No need to read all of the material unless you are interested.
 

Consider:

1) bacterial species that cause each infection
2) think about where a particular bacterial species lives (skin, water, soil) and how that impacts which disease it causes
3) what a bacteria needs to do to cause infection
4) what the host does to prevent infection, and how the bacteria gets around these defenses