61 yo female presented with large peripheral foci of necrotizing retinitis in the supratemporal quadrant in her left eye with positive serum toxoplasmosis titers which corresponded with a positive PCR for Toxoplasmosis on vitreous tap. She was subsequently treated with a 6 week course of azithromycin. She additionally was treated with Valacyclovir and Ganciclovir. The vitreous failed to clear with this course, and she developed a posterior subcapsular cataract. She then underwent a combined Phacoemulsification/IOL implant/Vitrectomy.